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Amphetamine is known to inhibit monoamine oxidase, Whilst the power of amphetamine and its metabolites to inhibit various P450 isozymes together with other enzymes hasn't been sufficiently elucidated. In vitro experiments with human microsomes point out insignificant inhibition of CYP2D6 by amphetamine and minimal inhibition of CYP1A2, 2D6, and 3A4